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Symbol
Name
ID
Notch3
notch 3
MGI:99460
Phenotype annotations related to endocrine/exocrine glands
Darker colors indicate more annotations
Human Phenotypes
Neoplasm of the pancreas
Disease(s) Associated with NOTCH3
infantile myofibromatosis

Mouse Phenotypes
decreased mammary gland epithelial cell proliferation
thymus hyperplasia
small thymus
decreased thymocyte number
increased thymocyte number
abnormal pancreas development
increased T cell derived lymphoma incidence
increased lymphoblastic lymphoma incidence
Availability Mouse Genotype
Notch3tm1Khan/Notch3tm1Khan
Tg(Lck-Notch3)#Issc/0
Tg(Pdx1-Notch3)1Heed/?
Gt(ROSA)26Sortm2(CAG-Dsred2/EGFP)Luo/Gt(ROSA)26Sortm1(Notch3*)Sfr
Notch3tm1.1(cre/ERT2)Sat/Notch3+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory